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Structure and Function of Cyclized Versions of the Proofreading Exonuclease Subunit of E. coli DNA Polymerase III

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	DNA polymerase III epsilon subunit	polymer	194	21618.6	1	UniProt (P03007) Pfam (PF00929) In PDB	Escherichia coli
2	A	MANGANESE (II) ION	non-polymer		54.9	2	Chemie (MN)
3	A	URIDINE-5'-MONOPHOSPHATE	non-polymer		324.2	2	Chemie (U5P)
4	A	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
5	A	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
6		water	water		18.0	240	Chemie (HOH)

Sequence modifications

A: 2 - 186 (UniProt: P03007)

PDB	External Database	Details
Ser -2	-	SEE REMARK 999
Ile -1	-	SEE REMARK 999
Glu 0	-	SEE REMARK 999
Phe 1	-	SEE REMARK 999
Thr 187	-	SEE REMARK 999
Arg 188	-	SEE REMARK 999
Glu 189	-	SEE REMARK 999
Ser 190	-	SEE REMARK 999
Gly 191	-	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	21618.6
Non-Polymers*	Number of molecules	7
	Total formula weight	988.5
All*	Total formula weight	22607.1

*Water molecules are not included.