2GNN
Crystal Structure of the Orf Virus NZ2 Variant of VEGF-E
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Vascular endothelial growth factor homolog | polymer | 127 | 14273.1 | 4 | UniProt (P52584) Pfam (PF00341) | Orf virus (strain NZ2) | |
| 2 | E, R, S (A, C) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 3 | F, T (A, C) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | G, N, X (A, B, D) | BENZAMIDINE | non-polymer | 120.2 | 3 | Chemie (BEN) | |||
| 5 | H, U (A, C) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 2 | Chemie (TRS) | |||
| 6 | I, J, K, L, O... (A, B, C) | GLYCEROL | non-polymer | 92.1 | 8 | Chemie (GOL) | |||
| 7 | M, W (B, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 8 | AA, BA, Y, Z (C, D, A, B) | water | water | 18.0 | 177 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 11 - 123 (UniProt: P52584)
| PDB | External Database | Details |
|---|---|---|
| Glu 5 | - | cloning artifact |
| Ala 6 | - | cloning artifact |
| Glu 7 | - | cloning artifact |
| Ala 8 | - | cloning artifact |
| Glu 9 | - | cloning artifact |
| Phe 10 | - | cloning artifact |
| Thr 77 | Ser 87 | SEE REMARK 999 |
| Val 124 | - | cloning artifact |
| Asp 125 | - | cloning artifact |
| His 126 | - | expression tag |
| His 127 | - | expression tag |
| His 128 | - | expression tag |
| His 129 | - | expression tag |
| His 130 | - | expression tag |
| His 131 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 57092.3 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 2082.4 | |
| All* | Total formula weight | 59174.7 |
