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2GNN

Crystal Structure of the Orf Virus NZ2 Variant of VEGF-E

Functional Information from GO Data
ChainGOidnamespacecontents
A0001666biological_processresponse to hypoxia
A0001938biological_processpositive regulation of endothelial cell proliferation
A0005172molecular_functionvascular endothelial growth factor receptor binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0007165biological_processsignal transduction
A0008083molecular_functiongrowth factor activity
A0016020cellular_componentmembrane
A0042056molecular_functionchemoattractant activity
A0050918biological_processpositive chemotaxis
A0050930biological_processinduction of positive chemotaxis
A0051781biological_processpositive regulation of cell division
B0001666biological_processresponse to hypoxia
B0001938biological_processpositive regulation of endothelial cell proliferation
B0005172molecular_functionvascular endothelial growth factor receptor binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0007165biological_processsignal transduction
B0008083molecular_functiongrowth factor activity
B0016020cellular_componentmembrane
B0042056molecular_functionchemoattractant activity
B0050918biological_processpositive chemotaxis
B0050930biological_processinduction of positive chemotaxis
B0051781biological_processpositive regulation of cell division
C0001666biological_processresponse to hypoxia
C0001938biological_processpositive regulation of endothelial cell proliferation
C0005172molecular_functionvascular endothelial growth factor receptor binding
C0005576cellular_componentextracellular region
C0005615cellular_componentextracellular space
C0007165biological_processsignal transduction
C0008083molecular_functiongrowth factor activity
C0016020cellular_componentmembrane
C0042056molecular_functionchemoattractant activity
C0050918biological_processpositive chemotaxis
C0050930biological_processinduction of positive chemotaxis
C0051781biological_processpositive regulation of cell division
D0001666biological_processresponse to hypoxia
D0001938biological_processpositive regulation of endothelial cell proliferation
D0005172molecular_functionvascular endothelial growth factor receptor binding
D0005576cellular_componentextracellular region
D0005615cellular_componentextracellular space
D0007165biological_processsignal transduction
D0008083molecular_functiongrowth factor activity
D0016020cellular_componentmembrane
D0042056molecular_functionchemoattractant activity
D0050918biological_processpositive chemotaxis
D0050930biological_processinduction of positive chemotaxis
D0051781biological_processpositive regulation of cell division
Functional Information from PROSITE/UniProt
site_idPS00249
Number of Residues13
DetailsPDGF_1 Platelet-derived growth factor (PDGF) family signature. PPCVtlmRCGGCC
ChainResidueDetails
APRO49-CYS61

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

246704

PDB entries from 2025-12-24

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