2GIR
Hepatitis C virus RNA-dependent RNA polymerase NS5B with NNI-1 inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | RNA-directed RNA polymerase | polymer | 568 | 63249.6 | 2 | UniProt (P26663) Pfam (PF00998) | Hepatitis C virus (isolate BK) | NS5B,p68 |
| 2 | C, D (A, B) | 3-{ISOPROPYL[(TRANS-4-METHYLCYCLOHEXYL)CARBONYL]AMINO}-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID | non-polymer | 385.5 | 2 | Chemie (NN3) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 566 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 562 (UniProt: P26663)
| PDB | External Database | Details |
|---|---|---|
| Met -5 | - | cloning artifact |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| His 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 126499.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 771.0 | |
| All* | Total formula weight | 127270.1 |
