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2G5R

Crystal structure of Siglec-7 in complex with methyl-9-(aminooxalyl-amino)-9-deoxyNeu5Ac (oxamido-Neu5Ac)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Sialic acid-binding Ig-like lectin 7polymer12714655.31UniProt (Q9Y286)
Pfam (PF07686)
Homo sapiens (human)Siglec-7, QA79 membrane protein, Adhesion inhibitory receptor molecule 1, AIRM-1, p75, D-siglec, CDw328 antigen
2B
(A)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.21Chemie (NAG)
3C
(A)
methyl 5-acetamido-9-{[amino(oxo)acetyl]amino}-3,5,9-trideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosidonic acidnon-polymer393.31Chemie (NXD)
4D
(A)
CYSTEINEnon-polymer121.21Chemie (CYS)
5E
(A)
waterwater18.0102Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight14655.3
Non-Polymers*Number of molecules3
Total formula weight735.7
All*Total formula weight15391.0
*Water molecules are not included.

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PDB entries from 2025-06-25

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