2G1M
Cellular Oxygen Sensing: Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase (PHD2)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Egl nine homolog 1 | polymer | 246 | 27525.3 | 1 | UniProt (Q9GZT9) Pfam (PF13640) | Homo sapiens (human) | Hypoxia-inducible factor prolyl hydroxylase 2, HIF-prolyl hydroxylase 2, HIF-PH2, HPH-2, Prolyl hydroxylase domain-containing protein 2, PHD2, SM-20 |
| 2 | B (A) | FE (II) ION | non-polymer | 55.8 | 1 | Chemie (FE2) | |||
| 3 | C (A) | N-[(4-HYDROXY-8-IODOISOQUINOLIN-3-YL)CARBONYL]GLYCINE | non-polymer | 372.1 | 1 | Chemie (4HG) | |||
| 4 | D (A) | water | water | 18.0 | 127 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27525.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 428.0 | |
| All* | Total formula weight | 27953.3 |
