2FVC
Crystal structure of NS5B BK strain (delta 24) in complex with a 3-(1,1-Dioxo-2H-(1,2,4)-benzothiadiazin-3-yl)-4-hydroxy-2(1H)-quinolinone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | polyprotein | polymer | 563 | 62432.6 | 2 | GenBank (12831193) Pfam (PF00998) UniProt (by SIFTS) (Q99AU2) In PDB | Hepatitis C virus subtype 1b | |
| 2 | A, B | 3-(1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-4-hydroxy-1-(3-methylbutyl)quinolin-2(1H)-one | non-polymer | 411.5 | 2 | Chemie (888) | |||
| 3 | water | water | 18.0 | 641 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 563 (GenBank: 12831193)
| PDB | External Database | Details |
|---|---|---|
| Val 329 | Thr 2748 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 124865.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 822.9 | |
| All* | Total formula weight | 125688.1 |
