2FVC
Crystal structure of NS5B BK strain (delta 24) in complex with a 3-(1,1-Dioxo-2H-(1,2,4)-benzothiadiazin-3-yl)-4-hydroxy-2(1H)-quinolinone
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003968 | molecular_function | RNA-dependent RNA polymerase activity |
| A | 0039694 | biological_process | viral RNA genome replication |
| B | 0003723 | molecular_function | RNA binding |
| B | 0003968 | molecular_function | RNA-dependent RNA polymerase activity |
| B | 0039694 | biological_process | viral RNA genome replication |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE 888 A 901 |
| Chain | Residue |
| A | PHE193 |
| A | TYR415 |
| A | TYR448 |
| A | GLY449 |
| A | SER556 |
| A | HOH904 |
| A | HOH921 |
| A | HOH1186 |
| A | ARG200 |
| A | ASN316 |
| A | CYS366 |
| A | SER368 |
| A | LEU384 |
| A | GLY410 |
| A | ASN411 |
| A | MET414 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE 888 B 902 |
| Chain | Residue |
| B | PHE193 |
| B | ARG200 |
| B | ASN316 |
| B | CYS366 |
| B | SER368 |
| B | LEU384 |
| B | GLY410 |
| B | ASN411 |
| B | MET414 |
| B | TYR415 |
| B | TYR448 |
| B | GLY449 |
| B | SER556 |
| B | HOH924 |
| B | HOH1201 |
| B | HOH1202 |
