2FTW

Crystal structure of dihydropyrimidinase from dictyostelium discoideum

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	dihydropyrimidine amidohydrolase	polymer	521	58342.9	1	UniProt (Q86LT2) Pfam (PF01979) UniProt (by SIFTS) (Q55DL0)	Dictyostelium discoideum	dihydropyrimidinase
2	B, C (A)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
3	D (A)	MALONATE ION	non-polymer		102.0	1	Chemie (MLI)
4	E (A)	water	water		18.0	280	Chemie (HOH)

Sequence modifications

A: 1 - 503 (UniProt: Q86LT2)

PDB	External Database	Details
Kcx 158	Lys 158	modified residue
Pro 504	-	expression tag
Gly 505	-	expression tag
Asp 506	-	expression tag
Asp 507	-	expression tag
Asp 508	-	expression tag
Asp 509	-	expression tag
Lys 510	-	expression tag
His 511	-	expression tag
His 512	-	expression tag
His 513	-	expression tag
His 514	-	expression tag
His 515	-	expression tag
His 516	-	expression tag
His 517	-	expression tag
His 518	-	expression tag
Ser 519	-	expression tag
Gly 520	-	expression tag
Asp 521	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	58342.9
Non-Polymers*	Number of molecules	3
	Total formula weight	232.9
All*	Total formula weight	58575.8

*Water molecules are not included.