2FSA
Crystal structure of PHD finger-linker-bromodomain fragment of human BPTF in the H3(1-15)K4ME2 bound state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | bromodomain PHD finger transcription factor | polymer | 174 | 20531.5 | 3 | UniProt (Q7Z7D6) Pfam (PF00628) Pfam (PF00439) UniProt (by SIFTS) (Q12830) In PDB | Homo sapiens (human) | |
| 2 | P | Histone H3(1-15)K4me2 peptide | polymer | 15 | 1592.8 | 1 | UniProt (by SIFTS) (P68431) In PDB | ||
| 3 | A, B, C | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 4 | water | water | 18.0 | 463 | Chemie (HOH) |
Sequence modifications
A, B, C: 6 - 174 (UniProt: Q7Z7D6)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | cloning artifact |
| Pro 2 | - | cloning artifact |
| Leu 3 | - | cloning artifact |
| Gly 4 | - | cloning artifact |
| Ser 5 | - | cloning artifact |
| Mse 63 | Met 2640 | modified residue |
| Mse 89 | Met 2666 | modified residue |
| Mse 113 | Met 2690 | modified residue |
| Mse 118 | Met 2695 | modified residue |
| Mse 137 | Met 2714 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 63187.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 392.5 | |
| All* | Total formula weight | 63579.9 |
