2FHJ
Crystal structure of formylmethanofuran: tetrahydromethanopterin formyltransferase in complex with its coenzymes
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Formylmethanofuran--tetrahydromethanopterin formyltransferase | polymer | 296 | 31686.4 | 3 | UniProt (Q49610) Pfam (PF01913) Pfam (PF02741) | Methanopyrus kandleri | H4MPT formyltransferase |
| 2 | D (D) | Formylmethanofuran--tetrahydromethanopterin formyltransferase | polymer | 296 | 31702.4 | 1 | UniProt (Q49610) Pfam (PF01913) Pfam (PF02741) | Methanopyrus kandleri | H4MPT formyltransferase |
| 3 | AA, BA, E, F, G... (D, A, B, C) | POTASSIUM ION | non-polymer | 39.1 | 17 | Chemie (K) | |||
| 4 | CA, I, J, V (D, A, C) | N-[4,5,7-TRICARBOXYHEPTANOYL]-L-GAMMA-GLUTAMYL-N-{2-[4-({5-[(FORMYLAMINO)METHYL]-3-FURYL}METHOXY)PHENYL]ETHYL}-D-GLUTAMINE | non-polymer | 776.7 | 4 | Chemie (MFN) | |||
| 5 | K, W (A, C) | 5-(4-{[1-(2-AMINO-5-FORMYL-7-METHYL-4-OXO-3,4,5,6,7,8-HEXAHYDROPTERIDIN-6-YL)ETHYL]AMINO}PHENYL)-5-DEOXY-1-O-{5-O-[(1,3-DICARBOXYPROPOXY)(HYDROXY)PHOSPHORYL]PENTOFURANOSYL}PENTITOL | non-polymer | 804.7 | 2 | Chemie (H4Z) | |||
| 6 | DA, EA, L (D, A) | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL | non-polymer | 354.4 | 3 | Chemie (PE4) | |||
| 7 | X (C) | 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL | non-polymer | 634.8 | 1 | Chemie (PE3) | |||
| 8 | FA, GA, HA, IA (A, B, C, D) | water | water | 18.0 | 451 | Chemie (HOH) |
Sequence modifications
D: 1 - 296 (UniProt: Q49610)
| PDB | External Database | Details |
|---|---|---|
| Cso 58 | Cys 58 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 126761.8 | |
| Non-Polymers* | Number of molecules | 27 |
| Total formula weight | 7079.1 | |
| All* | Total formula weight | 133840.9 |
