2FDB
Crystal Structure of Fibroblast growth factor (FGF)8b in complex with FGF Receptor (FGFR) 2c
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (M, N) | fibroblast growth factor 8 isoform B | polymer | 164 | 18906.6 | 2 | UniProt (P55075) Pfam (PF00167) | Homo sapiens (human) | FGF8b |
| 2 | B, D (P, R) | Fibroblast growth factor receptor 2 | polymer | 220 | 24758.1 | 2 | UniProt (Q9UQH9) Pfam (PF07679) Pfam (PF13927) UniProt (by SIFTS) (P21802) | Homo sapiens (human) | FGFR2c; FGFR-2; Keratinocyte growth factor receptor 2; CD332 antigen |
| 3 | E, F, G, H (M, P, N, R) | water | water | 18.0 | 125 | Chemie (HOH) |
Sequence modifications
P, R: 2149 - 2368 (UniProt: Q9UQH9)
| PDB | External Database | Details |
|---|---|---|
| Arg 2253 | Pro 253 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 87329.6 | |
| All* | Total formula weight | 87329.6 |
