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2F4B

Crystal structure of the ligand binding domain of human PPAR-gamma in complex with an agonist

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Peroxisome proliferator-activated receptor gammapolymer27130997.02UniProt (P37231)
Pfam (PF00104)
Homo sapiens (human)PPAR-gamma
2C
(A)
(5-{3-[(6-BENZOYL-1-PROPYL-2-NAPHTHYL)OXY]PROPOXY}-1H-INDOL-1-YL)ACETIC ACIDnon-polymer521.61Chemie (EHA)
3D, E
(A, B)
waterwater18.0140Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight61994.0
Non-Polymers*Number of molecules1
Total formula weight521.6
All*Total formula weight62515.6
*Water molecules are not included.

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PDB entries from 2025-06-11

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