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2F4B

Crystal structure of the ligand binding domain of human PPAR-gamma in complex with an agonist

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0005634cellular_componentnucleus
A0006355biological_processregulation of DNA-templated transcription
B0003677molecular_functionDNA binding
B0004879molecular_functionnuclear receptor activity
B0005634cellular_componentnucleus
B0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues17
DetailsBINDING SITE FOR RESIDUE EHA A 201
ChainResidue
ALEU255
ALEU330
AILE341
AMET348
APHE363
AMET364
ALYS367
AHIS449
ATYR473
AGLU259
AARG280
APHE282
AGLY284
ACYS285
AGLN286
ASER289
ATYR327

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsBINDING: BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG
ChainResidueDetails
AGLN286
AHIS323
AHIS449
ATYR473
BGLN286
BHIS323
BHIS449
BTYR473

217705

PDB entries from 2024-03-27

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