2F36
Crystal Structure of the GluR5 Ligand Binding Core Dimer with Glutamate At 2.1 Angstroms Resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 1 | polymer | 258 | 29211.5 | 4 | UniProt (P22756) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Norway rat) | Glutamate receptor 5, GluR-5, GluR5 |
| 2 | E, J, K, L (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | F, G, H, I (A) | GLUTAMIC ACID | non-polymer | 147.1 | 4 | Chemie (GLU) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 439 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 3 - 116 (UniProt: P22756)
A, B, C, D: 119 - 258 (UniProt: P22756)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | cloning artifact |
| Ser 2 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 117 | - | linker |
| Thr 118 | - | linker |
| Ser 258 | Glu 821 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 116846.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 972.8 | |
| All* | Total formula weight | 117818.9 |
