2F36
Crystal Structure of the GluR5 Ligand Binding Core Dimer with Glutamate At 2.1 Angstroms Resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| A | 0016020 | cellular_component | membrane |
| B | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| B | 0016020 | cellular_component | membrane |
| C | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| C | 0016020 | cellular_component | membrane |
| D | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| D | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 601 |
| Chain | Residue |
| A | ARG227 |
| B | GLY223 |
| B | ARG227 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 D 602 |
| Chain | Residue |
| C | ARG227 |
| D | ARG227 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 603 |
| Chain | Residue |
| A | PRO257 |
| C | MET106 |
| C | THR107 |
| D | SER213 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 604 |
| Chain | Residue |
| A | MET106 |
| A | THR107 |
| A | HOH714 |
| B | SER213 |
| C | PRO257 |
| site_id | AC5 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE GLU A 501 |
| Chain | Residue |
| A | TYR61 |
| A | PRO88 |
| A | LEU89 |
| A | THR90 |
| A | ARG95 |
| A | GLY140 |
| A | SER141 |
| A | THR142 |
| A | GLU190 |
| A | TYR216 |
| A | HOH606 |
| A | HOH609 |
| A | HOH610 |
| A | HOH620 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE GLU A 502 |
| Chain | Residue |
| A | HOH605 |
| B | TYR61 |
| B | PRO88 |
| B | LEU89 |
| B | THR90 |
| B | ARG95 |
| B | GLY140 |
| B | SER141 |
| B | THR142 |
| B | GLU190 |
| B | HOH603 |
| B | HOH608 |
| site_id | AC7 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE GLU A 503 |
| Chain | Residue |
| A | HOH615 |
| C | TYR61 |
| C | PRO88 |
| C | LEU89 |
| C | THR90 |
| C | ARG95 |
| C | GLY140 |
| C | SER141 |
| C | THR142 |
| C | GLU190 |
| C | TYR216 |
| C | HOH610 |
| C | HOH615 |
| C | HOH654 |
| site_id | AC8 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GLU A 504 |
| Chain | Residue |
| A | HOH664 |
| D | TYR61 |
| D | PRO88 |
| D | LEU89 |
| D | THR90 |
| D | ARG95 |
| D | GLY140 |
| D | SER141 |
| D | THR142 |
| D | GLU190 |
| D | HOH632 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15710405","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1YCJ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15710405","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15721240","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1YCJ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine; by PKC","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphothreonine; by PKC","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
