2EC0

RNA-dependent RNA polymerase of foot-and-mouth disease virus in complex with a template-primer RNA and ATP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (B, E)	5'-R(P*AP*UP*GP*GP*GP*CP*CP*C)-3'	polymer	8	2541.6	2
2	B, D (C, F)	5'-R(*GP*GP*GP*CP*CP*CP*A)-3'	polymer	7	2235.4	2
3	E, F (A, D)	RNA-dependent RNA polymerase	polymer	476	53486.7	2	UniProt (Q0QEE1) Pfam (PF00680) UniProt (by SIFTS) (Q9QCE4)	Foot-and-mouth disease virus C-S8c1
4	G, I (A, D)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
5	H, J (A, D)	PYROPHOSPHATE	non-polymer		178.0	2	Chemie (PPV)
6	K, L, M, N, O... (B, C, E, F, A...)	water	water		18.0	114	Chemie (HOH)

Sequence modifications

A, D: 1 - 470 (UniProt: Q0QEE1)

PDB	External Database	Details
Ala 471	-	cloning artifact
Ala 472	-	cloning artifact
Leu 473	-	cloning artifact
Glu 474	-	cloning artifact
His 475	-	cloning artifact
His 476	-	cloning artifact

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	116527.3
Non-Polymers*	Number of molecules	4
	Total formula weight	404.6
All*	Total formula weight	116931.9

*Water molecules are not included.