2E0A
Crystal structure of human pyruvate dehydrogenase kinase 4 in complex with AMPPNP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Pyruvate dehydrogenase kinase isozyme 4 | polymer | 394 | 44771.0 | 2 | UniProt (Q16654) Pfam (PF10436) Pfam (PF02518) In PDB | Homo sapiens (human) | Pyruvate dehydrogenase kinase 4 |
| 2 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | A, B | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 2 | Chemie (ANP) | |||
| 4 | water | water | 18.0 | 311 | Chemie (HOH) |
Sequence modifications
A, B: 20 - 411 (UniProt: Q16654)
| PDB | External Database | Details |
|---|---|---|
| Gly 18 | - | expression tag |
| Pro 19 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 89542.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1061.0 | |
| All* | Total formula weight | 90603.0 |
