2DVS
Crystal structure analysis of the N-terminal bromodomain of human BRD2 complexed with acetylated histone H4 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | bromodomain-containing protein 2 | polymer | 122 | 14800.1 | 3 | UniProt (P25440) Pfam (PF00439) | Homo sapiens (human) | RING3 protein, O27.1.1 |
| 2 | D, E (P, Q) | histone H4 | polymer | 12 | 1353.6 | 2 | |||
| 3 | F, G, H, I, J (A, B, C, P, Q) | water | water | 18.0 | 250 | Chemie (HOH) |
Sequence modifications
A, B, C: 7 - 128 (UniProt: P25440)
| PDB | External Database | Details |
|---|---|---|
| Mse 21 | Met 87 | modified residue |
| Mse 55 | Met 121 | modified residue |
| Mse 57 | Met 123 | modified residue |
| Mse 76 | Met 142 | modified residue |
| Mse 82 | Met 148 | modified residue |
| Mse 99 | Met 165 | modified residue |
| Mse 114 | Met 180 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 47107.7 | |
| All* | Total formula weight | 47107.7 |
