2DVS

Crystal structure analysis of the N-terminal bromodomain of human BRD2 complexed with acetylated histone H4 peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	bromodomain-containing protein 2	polymer	122	14800.1	3	UniProt (P25440) Pfam (PF00439) In PDB	Homo sapiens (human)	RING3 protein, O27.1.1
2	P, Q	histone H4	polymer	12	1353.6	2
3		water	water		18.0	250	Chemie (HOH)

Sequence modifications

A, B, C: 7 - 128 (UniProt: P25440)

PDB	External Database	Details
Mse 21	Met 87	modified residue
Mse 55	Met 121	modified residue
Mse 57	Met 123	modified residue
Mse 76	Met 142	modified residue
Mse 82	Met 148	modified residue
Mse 99	Met 165	modified residue
Mse 114	Met 180	modified residue

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	47107.7
All*	Total formula weight	47107.7

*Water molecules are not included.