2DRD
Crystal structure of a multidrug transporter reveal a functionally rotating mechanism
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | ACRB | polymer | 1053 | 114217.7 | 3 | UniProt (P31224) Pfam (PF00873) | Escherichia coli | multidrug efflux transporter, Acriflavine resistance protein B |
| 2 | D (A) | (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE | non-polymer | 457.5 | 1 | Chemie (MIY) |
Sequence modifications
A, B, C: 1 - 1049 (UniProt: P31224)
| PDB | External Database | Details |
|---|---|---|
| His 1050 | - | expression tag |
| His 1051 | - | expression tag |
| His 1052 | - | expression tag |
| His 1053 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 342653.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 457.5 | |
| All* | Total formula weight | 343110.7 |
