2D39

Trivalent Recognition Unit of Innate Immunity System; Crystal Structure of human M-ficolin Fibrinogen-like Domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Ficolin-1	polymer	237	26864.6	3	UniProt (O00602) Pfam (PF00147)	Homo sapiens (human)	Collagen/fibrinogen domain-containing protein 1, Ficolin-A, Ficolin A, M-Ficolin
2	D, E (A, C)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
3	F, G, H (A, B, C)	water	water		18.0	283	Chemie (HOH)

Sequence modifications

A, B, C: 115 - 326 (UniProt: O00602)

PDB	External Database	Details
Glu 113	-	cloning artifact
Phe 114	-	cloning artifact
Phe 327	-	cloning artifact
Leu 328	-	cloning artifact
Glu 329	-	SEE REMARK 999
Gln 330	-	SEE REMARK 999
Lys 331	-	SEE REMARK 999
Leu 332	-	SEE REMARK 999
Ile 333	-	SEE REMARK 999
Ser 334	-	SEE REMARK 999
Glu 335	-	SEE REMARK 999
Glu 336	-	SEE REMARK 999
Asp 337	-	SEE REMARK 999
Leu 338	-	SEE REMARK 999
Asn 339	-	cloning artifact
Ser 340	-	cloning artifact
Ala 341	-	cloning artifact
Val 342	-	cloning artifact
Asp 343	-	cloning artifact
His 344	-	expression tag
His 345	-	expression tag
His 346	-	expression tag
His 347	-	expression tag
His 348	-	expression tag
His 349	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	80593.9
Non-Polymers*	Number of molecules	2
	Total formula weight	80.2
All*	Total formula weight	80674.1

*Water molecules are not included.