2D39
Trivalent Recognition Unit of Innate Immunity System; Crystal Structure of human M-ficolin Fibrinogen-like Domain
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 1401 |
| Chain | Residue |
| A | ASP262 |
| A | ASP264 |
| A | SER266 |
| A | SER268 |
| A | HOH1402 |
| A | HOH1403 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 2401 |
| Chain | Residue |
| C | SER266 |
| C | SER268 |
| C | HOH2402 |
| B | GLY250 |
| C | ASP262 |
| C | ASP264 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:17148457, ECO:0000269|PubMed:17897951, ECO:0000269|PubMed:20032467, ECO:0007744|PDB:2D39, ECO:0007744|PDB:2WNP |
| Chain | Residue | Details |
| A | ASP262 | |
| C | ASP264 | |
| C | SER266 | |
| C | SER268 | |
| A | ASP264 | |
| A | SER266 | |
| A | SER268 | |
| B | ASP262 | |
| B | ASP264 | |
| B | SER266 | |
| B | SER268 | |
| C | ASP262 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:17897951 |
| Chain | Residue | Details |
| A | ASP282 | |
| B | ASP282 | |
| C | ASP282 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | SITE: Mediates specificity for sialic acids => ECO:0000305|PubMed:17897951, ECO:0000305|PubMed:20032467 |
| Chain | Residue | Details |
| A | TYR300 | |
| B | TYR300 | |
| C | TYR300 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | SITE: Mediates specificity for sialic acids => ECO:0000305|PubMed:17897951 |
| Chain | Residue | Details |
| A | TYR312 | |
| B | TYR312 | |
| C | TYR312 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN305 | |
| B | ASN305 | |
| C | ASN305 |
