2D39
Trivalent Recognition Unit of Innate Immunity System; Crystal Structure of human M-ficolin Fibrinogen-like Domain
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 1401 |
| Chain | Residue |
| A | ASP262 |
| A | ASP264 |
| A | SER266 |
| A | SER268 |
| A | HOH1402 |
| A | HOH1403 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 2401 |
| Chain | Residue |
| C | SER266 |
| C | SER268 |
| C | HOH2402 |
| B | GLY250 |
| C | ASP262 |
| C | ASP264 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 117 |
| Details | Region: {"description":"A domain; contributes to trimerization"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 264 |
| Details | Region: {"description":"B domain; contributes to trimerization"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 27 |
| Details | Region: {"description":"P domain","evidences":[{"source":"PubMed","id":"17148457","evidenceCode":"ECO:0000303"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17148457","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17897951","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20032467","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2D39","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2WNP","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17897951","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Site: {"description":"Mediates specificity for sialic acids","evidences":[{"source":"PubMed","id":"17897951","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 3 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Site: {"description":"Mediates specificity for sialic acids","evidences":[{"source":"PubMed","id":"17897951","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"20032467","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
