2CL0
CRYSTAL STRUCTURE ANALYSIS OF A FLUORESCENT FORM OF H-RAS P21 IN COMPLEX WITH GppNHp
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (X) | GTPASE HRAS | polymer | 166 | 18799.1 | 1 | UniProt (P01112) Pfam (PF00071) | HOMO SAPIENS (HUMAN) | TRANSFORMING PROTEIN P21, P21RAS, H-RAS-1, C-H-RAS |
| 2 | B, C, D, E, F (X) | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) | |||
| 3 | G (X) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 4 | H (X) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 1 | Chemie (GNP) | |||
| 5 | I (X) | N,N'-DIMETHYL-N-(ACETYL)-N'-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)ETHYLENEDIAMINE | non-polymer | 293.3 | 1 | Chemie (XY2) | |||
| 6 | J (X) | water | water | 18.0 | 168 | Chemie (HOH) |
Sequence modifications
X: 1 - 166 (UniProt: P01112)
| PDB | External Database | Details |
|---|---|---|
| Cys 32 | Tyr 32 | engineered mutation |
| Ser 118 | Cys 118 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18799.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1059.1 | |
| All* | Total formula weight | 19858.2 |
