2CG5

Structure of aminoadipate-semialdehyde dehydrogenase- phosphopantetheinyl transferase in complex with cytosolic acyl carrier protein and coenzyme A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINYL TRANSFERASE	polymer	319	37051.9	1	UniProt (Q9NRN7) Pfam (PF01648) In PDB	HOMO SAPIENS (HUMAN)	4'-PHOSPHOPANTETHEINYL TRANSFERASE, ALPHA- AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE- PHOSPHOPANTETHEINYL TRANSFERASE, AASD-PPT, LYS5 ORTHOLOG
2	B	FATTY ACID SYNTHASE	polymer	91	10065.4	1	UniProt (P49327) Pfam (PF00550) In PDB	HOMO SAPIENS (HUMAN)	ACYL-CARRIER-PROTEIN
3	A	COENZYME A	non-polymer		767.5	1	Chemie (COA)
4	A	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
5	A	NICKEL (II) ION	non-polymer		58.7	1	Chemie (NI)
6	A	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
7		water	water		18.0	24	Chemie (HOH)

Sequence modifications

A: 1 - 23 (PDB: 2CG5)
A: 24 - 319 (UniProt: Q9NRN7)
B: 2117 - 2118 (PDB: 2CG5)
B: 2119 - 2207 (UniProt: P49327)

PDB	External Database	Details
Ala 2156	Ser 2156	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	47117.3
Non-Polymers*	Number of molecules	5
	Total formula weight	969.8
All*	Total formula weight	48087.1

*Water molecules are not included.