2CG5
Structure of aminoadipate-semialdehyde dehydrogenase- phosphopantetheinyl transferase in complex with cytosolic acyl carrier protein and coenzyme A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINYL TRANSFERASE | polymer | 319 | 37051.9 | 1 | UniProt (Q9NRN7) Pfam (PF22624) Pfam (PF01648) | HOMO SAPIENS (HUMAN) | 4'-PHOSPHOPANTETHEINYL TRANSFERASE, ALPHA- AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE- PHOSPHOPANTETHEINYL TRANSFERASE, AASD-PPT, LYS5 ORTHOLOG |
| 2 | B (B) | FATTY ACID SYNTHASE | polymer | 91 | 10065.4 | 1 | UniProt (P49327) Pfam (PF00550) | HOMO SAPIENS (HUMAN) | ACYL-CARRIER-PROTEIN |
| 3 | C (A) | COENZYME A | non-polymer | 767.5 | 1 | Chemie (COA) | |||
| 4 | D, G (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | E (A) | NICKEL (II) ION | non-polymer | 58.7 | 1 | Chemie (NI) | |||
| 6 | F (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 7 | H, I (A, B) | water | water | 18.0 | 24 | Chemie (HOH) |
Sequence modifications
A: 1 - 23 (PDB: 2CG5)
A: 24 - 319 (UniProt: Q9NRN7)
B: 2117 - 2118 (PDB: 2CG5)
B: 2119 - 2207 (UniProt: P49327)
A: 24 - 319 (UniProt: Q9NRN7)
B: 2117 - 2118 (PDB: 2CG5)
B: 2119 - 2207 (UniProt: P49327)
| PDB | External Database | Details |
|---|---|---|
| Ala 2156 | Ser 2156 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47117.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 969.8 | |
| All* | Total formula weight | 48087.1 |
