2C7R
HhaI DNA methyltransferase (T250G mutant) complex with oligonucleotide containing 2-aminopurine as a target base (GPGC:GMGC) and SAH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | MODIFICATION METHYLASE HHAI | polymer | 327 | 36998.2 | 1 | UniProt (P05102) Pfam (PF00145) | HAEMOPHILUS HAEMOLYTICUS | DNA METHYLTRANSFERASE HHAI, CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI |
| 2 | B (C) | 5'-D(*G*GP*AP*TP*GP*(5CM)*GP*CP*TP*GP*AP*C)-3' | polymer | 12 | 3717.4 | 1 | SYNTHETIC CONSTRUCT | ||
| 3 | C (D) | 5'-D(*G*TP*CP*AP*GP*(2PR)*GP*CP*AP*TP*CP*C)-3' | polymer | 12 | 3647.4 | 1 | SYNTHETIC CONSTRUCT | ||
| 4 | D (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
| 5 | E, F, G, H, I... (A) | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
| 6 | L, M, N, O, P (A) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 7 | Q, R, S (A, C, D) | water | water | 18.0 | 271 | Chemie (HOH) |
Sequence modifications
A: 1 - 327 (UniProt: P05102)
| PDB | External Database | Details |
|---|---|---|
| Gly 250 | Thr 250 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 44363.0 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1517.3 | |
| All* | Total formula weight | 45880.3 |
