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2C05

Crystal Structures of Eosinophil-derived Neurotoxin in Complex with the Inhibitors 5'-ATP, Ap3A, Ap4A and Ap5A

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
NONSECRETORY RIBONUCLEASEpolymer13515611.81UniProt (P10153)
Pfam (PF00074)
HOMO SAPIENS (HUMAN)EOSINOPHIL-DERIVED NEUROTOXIN, RIBONUCLEASE US, RNASE UPI-2, RIBONUCLEASE 2, RNASE 2
2B
(A)
ACETIC ACIDnon-polymer60.11Chemie (ACY)
3C
(A)
BIS(ADENOSINE)-5'-TETRAPHOSPHATEnon-polymer836.41Chemie (B4P)
PubChem (24867496)
PubChem (44286171)
PubChem (54592217)
PubChem (58298222)
PubChem (194)
PubChem (6328499)
PubChem (21706)
PubChem (10795591)
PubChem (13455593)
PubChem (118705482)
PubChem (6603812)
PubChem (11513435)
PubChem (11957522)
PubChem (13455592)
PubChem (146121073)
PubChem (171904579)
4D
(A)
waterwater18.0119Chemie (HOH)
Sequence modifications
A: 0 - 0 (PDB: 2C05)
A: 1 - 134 (UniProt: P10153)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight15611.8
Non-Polymers*Number of molecules2
Total formula weight896.4
All*Total formula weight16508.2
*Water molecules are not included.

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PDB entries from 2026-04-01

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