2BU5
crystal structures of human pyruvate dehydrogenase kinase 2 containing physiological and synthetic ligands
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | PYRUVATE DEHYDROGENASE KINASE ISOENZYME 2 | polymer | 394 | 44647.7 | 1 | UniProt (Q15119) Pfam (PF10436) Pfam (PF02518) In PDB | HOMO SAPIENS (HUMAN) | PYRUVATE DEHYDROGENASE KINASE ISOFORM 2 |
2 | A | 4-({(2R,5S)-2,5-DIMETHYL-4-[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]PIPERAZIN-1-YL}CARBONYL)BENZONITRILE | non-polymer | 383.4 | 1 | Chemie (TF1) | |||
3 | water | water | 18.0 | 108 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 44647.7 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 383.4 | |
All* | Total formula weight | 45031.1 |