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2BME

high resolution structure of GppNHp-bound human Rab4a

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
RAS-RELATED PROTEIN RAB4Apolymer18620990.84UniProt (P20338)
Pfam (PF00071)
HOMO SAPIENS (HUMAN)RAB4A
2E, J, L, Q
(A, B, C, D)
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTERnon-polymer522.24Chemie (GNP)
3F, G, M, P
(A, C, D)
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOLnon-polymer122.14Chemie (TRS)
4H, N
(A, C)
BETA-MERCAPTOETHANOLnon-polymer78.12Chemie (BME)
5I, K, O, R
(A, B, C, D)
MAGNESIUM IONnon-polymer24.34Chemie (MG)
6S, T, U, V
(A, B, C, D)
waterwater18.0684Chemie (HOH)
Sequence modifications
A, B, C, D: 1 - 2 (PDB: 2BME)
A, B, C, D: 3 - 186 (UniProt: P20338)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight83963.1
Non-Polymers*Number of molecules14
Total formula weight2830.8
All*Total formula weight86793.9
*Water molecules are not included.

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PDB entries from 2025-07-30

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