2B4Y
Crystal Structure of Human Sirtuin homolog 5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | NAD-dependent deacetylase sirtuin-5 | polymer | 271 | 29567.2 | 4 | UniProt (Q9NXA8) Pfam (PF02146) In PDB | Homo sapiens (human) | SIR2-like protein 5 |
| 2 | A, B, C, D | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | A, B, C, D | ADENOSINE-5-DIPHOSPHORIBOSE | non-polymer | 559.3 | 4 | Chemie (APR) | |||
| 4 | A, B, C, D | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 4 | Chemie (EPE) | |||
| 5 | water | water | 18.0 | 707 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 34 - 302 (UniProt: Q9NXA8)
| PDB | External Database | Details |
|---|---|---|
| Gly 32 | - | cloning artifact |
| Ser 33 | - | cloning artifact |
| Mse 40 | Met 40 | modified residue |
| Mse 109 | Met 109 | modified residue |
| Mse 259 | Met 259 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 118268.8 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 3452.1 | |
| All* | Total formula weight | 121720.9 |
