2B2X
VLA1 RdeltaH I-domain complexed with a quadruple mutant of the AQC2 Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, B) | Integrin alpha-1 | polymer | 223 | 24986.2 | 2 | UniProt (P18614) Pfam (PF00092) | Rattus norvegicus (Norway rat) | Laminin and collagen receptor, VLA-1, CD49a |
| 2 | B, E (H, I) | Antibody AQC2 Fab | polymer | 226 | 24222.0 | 2 | Mus musculus (house mouse) | ||
| 3 | C, F (L, M) | Antibody AQC2 Fab | polymer | 213 | 23588.9 | 2 | Mus musculus (house mouse) | ||
| 4 | G, H (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | I, J, K, L, M... (A, H, L, B, I...) | water | water | 18.0 | 226 | Chemie (HOH) |
Sequence modifications
A, B: 127 - 340 (UniProt: P18614)
| PDB | External Database | Details |
|---|---|---|
| Gly 125 | - | cloning artifact |
| Ser 126 | - | cloning artifact |
| Val 217 | Gly 241 | engineered mutation |
| Gln 218 | Arg 242 | engineered mutation |
| Arg 219 | Gln 243 | engineered mutation |
| Arg 222 | Leu 246 | engineered mutation |
| Leu 341 | - | cloning artifact |
| Glu 342 | - | cloning artifact |
| Arg 343 | - | cloning artifact |
| Pro 344 | - | cloning artifact |
| His 345 | - | cloning artifact |
| Arg 346 | - | cloning artifact |
| Asp 347 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 145594.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 48.6 | |
| All* | Total formula weight | 145643.0 |
