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2AOV

Histamine Methyltransferase Complexed with the Antifolate Drug Metoprine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Histamine N-methyltransferasepolymer29233333.02UniProt (P50135)
Pfam (PF13489)
Homo sapiens (human)HMT
2C, E
(A, B)
4-(DIMETHYLAMINO)BUTYL IMIDOTHIOCARBAMATEnon-polymer175.32Chemie (4DI)
3D, F
(A, B)
5-(3,4-DICHLOROPHENYL)-6-METHYLPYRIMIDINE-2,4-DIAMINEnon-polymer269.12Chemie (C2M)
4G, H
(A, B)
waterwater18.091Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight66666.0
Non-Polymers*Number of molecules4
Total formula weight888.8
All*Total formula weight67554.9
*Water molecules are not included.

237735

PDB entries from 2025-06-18

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