2AOV

Histamine Methyltransferase Complexed with the Antifolate Drug Metoprine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Histamine N-methyltransferase	polymer	292	33333.0	2	UniProt (P50135) Pfam (PF13489) In PDB	Homo sapiens (human)	HMT
2	A, B	4-(DIMETHYLAMINO)BUTYL IMIDOTHIOCARBAMATE	non-polymer		175.3	2	Chemie (4DI)
3	A, B	5-(3,4-DICHLOROPHENYL)-6-METHYLPYRIMIDINE-2,4-DIAMINE	non-polymer		269.1	2	Chemie (C2M)
4		water	water		18.0	91	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	66666.0
Non-Polymers*	Number of molecules	4
	Total formula weight	888.8
All*	Total formula weight	67554.9

*Water molecules are not included.