2ANN
Crystal structure (I) of Nova-1 KH1/KH2 domain tandem with 25 nt RNA hairpin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (B) | 5'-R(*CP*GP*CP*GP*CP*GP*GP*AP*UP*CP*AP*GP*UP*CP*AP*CP*CP*CP*AP*AP*GP*CP*GP*CP*G)-3' | polymer | 25 | 8026.9 | 1 | |||
2 | B (A) | RNA-binding protein Nova-1 | polymer | 178 | 19189.0 | 1 | UniProt (Q9JKN6) Pfam (PF00013) UniProt (by SIFTS) (P51513) | Mus musculus (Mouse) | Neuro-oncological ventral antigen 1,Ventral neuron-specific protein 1 |
3 | C (B) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
4 | D, E (B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
5 | F, G (B, A) | water | water | 18.0 | 77 | Chemie (HOH) |
Sequence modifications
A: 5 - 178 (UniProt: Q9JKN6)
PDB | External Database | Details |
---|---|---|
Pro 1 | - | expression tag |
Leu 2 | - | expression tag |
Gly 3 | - | expression tag |
Ser 4 | - | expression tag |
- | Arg 146 | deletion |
- | Ile 147 | deletion |
- | Lys 148 | deletion |
- | Gln 149 | deletion |
- | Thr 150 | deletion |
- | Leu 151 | deletion |
- | Pro 152 | deletion |
- | Ser 153 | deletion |
- | Ser 154 | deletion |
- | Pro 155 | deletion |
- | Thr 156 | deletion |
- | Thr 157 | deletion |
- | Thr 158 | deletion |
- | Lys 159 | deletion |
- | Ser 160 | deletion |
- | Ser 161 | deletion |
- | Pro 162 | deletion |
- | Ser 163 | deletion |
- | Asp 164 | deletion |
- | Pro 165 | deletion |
- | Met 166 | deletion |
- | Thr 167 | deletion |
- | Thr 168 | deletion |
- | Ser 169 | deletion |
Asn 150 | Glu 218 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 27215.9 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 87.7 | |
All* | Total formula weight | 27303.6 |