2AL4
CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH quisqualate and CX614.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Glutamate receptor 2 | polymer | 263 | 29221.7 | 6 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Norway rat) | GluR-2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2 |
| 2 | G, I, J, L, M... (A, B, C, D, E...) | ZINC ION | non-polymer | 65.4 | 10 | Chemie (ZN) | |||
| 3 | H, K, O, Q, U... (A, B, C, D, E...) | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID | non-polymer | 189.1 | 6 | Chemie (QUS) | |||
| 4 | N, T, X (C, E, F) | 2,3,6A,7,8,9-HEXAHYDRO-11H-[1,4]DIOXINO[2,3-G]PYRROLO[2,1-B][1,3]BENZOXAZIN-11-ONE | non-polymer | 247.2 | 3 | Chemie (CX6) | |||
| 5 | AA, BA, CA, DA, EA... (B, C, D, E, F...) | water | water | 18.0 | 776 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 3 - 117 (UniProt: P19491)
A, B, C, D, E, F: 120 - 263 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | cloning artifact |
| Ala 2 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 118 | - | SEE REMARK 999 |
| Thr 119 | - | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 175330.1 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 2530.6 | |
| All* | Total formula weight | 177860.7 |
