2ACL
Liver X-Receptor alpha Ligand Binding Domain with SB313987
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, E, G) | Retinoic acid receptor RXR-alpha | polymer | 238 | 26667.9 | 4 | UniProt (P19793) Pfam (PF00104) | Homo sapiens (human) | Retinoid X receptor alpha |
| 2 | B, D, F, H (B, D, F, H) | Oxysterols receptor LXR-alpha | polymer | 244 | 28189.2 | 4 | UniProt (Q9Z0Y9) Pfam (PF00104) | Mus musculus (house mouse) | Liver X receptor alpha, Nuclear orphan receptor LXR-alpha |
| 3 | I, K, M, O (A, C, E, G) | RETINOIC ACID | non-polymer | 300.4 | 4 | Chemie (REA) PubChem (5538) PubChem (23275881) PubChem (25145416) PubChem (444795) PubChem (449171) PubChem (5282379) PubChem (6336207) PubChem (6336229) PubChem (6419708) PubChem (87179195) PubChem (87519764) PubChem (87980058) PubChem (88439848) PubChem (88525859) PubChem (88604688) PubChem (6603983) PubChem (9796370) PubChem (9861147) PubChem (445925) PubChem (10881132) PubChem (12358677) PubChem (12358678) PubChem (12358679) PubChem (12358681) PubChem (134688661) PubChem (139597075) PubChem (145826768) PubChem (166478803) | |||
| 4 | J, L, N, P (B, D, F, H) | 1-BENZYL-3-(4-METHOXYPHENYLAMINO)-4-PHENYLPYRROLE-2,5-DIONE | non-polymer | 384.4 | 4 | Chemie (L05) PubChem (5288679) | |||
| 5 | Q, R, S, T, U... (A, B, C, D, E...) | water | water | 18.0 | 36 | Chemie (HOH) |
Sequence modifications
B, D, F, H: 203 - 445 (UniProt: Q9Z0Y9)
| PDB | External Database | Details |
|---|---|---|
| Val 202 | - | cloning artifact |
| Pro 399 | Arg 399 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 219428.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2739.4 | |
| All* | Total formula weight | 222167.9 |
