2ACL
Liver X-Receptor alpha Ligand Binding Domain with SB313987
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, E, G) | Retinoic acid receptor RXR-alpha | polymer | 238 | 26667.9 | 4 | UniProt (P19793) Pfam (PF00104) | Homo sapiens (human) | Retinoid X receptor alpha |
| 2 | B, D, F, H (B, D, F, H) | Oxysterols receptor LXR-alpha | polymer | 244 | 28189.2 | 4 | UniProt (Q9Z0Y9) Pfam (PF00104) | Mus musculus (house mouse) | Liver X receptor alpha, Nuclear orphan receptor LXR-alpha |
| 3 | I, K, M, O (A, C, E, G) | RETINOIC ACID | non-polymer | 300.4 | 4 | Chemie (REA) | |||
| 4 | J, L, N, P (B, D, F, H) | 1-BENZYL-3-(4-METHOXYPHENYLAMINO)-4-PHENYLPYRROLE-2,5-DIONE | non-polymer | 384.4 | 4 | Chemie (L05) | |||
| 5 | Q, R, S, T, U... (A, B, C, D, E...) | water | water | 18.0 | 36 | Chemie (HOH) |
Sequence modifications
B, D, F, H: 203 - 445 (UniProt: Q9Z0Y9)
| PDB | External Database | Details |
|---|---|---|
| Val 202 | - | cloning artifact |
| Pro 399 | Arg 399 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 219428.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2739.4 | |
| All* | Total formula weight | 222167.9 |
