2ABI
Crystal structure of the human mineralocorticoid receptor ligand-binding domain bound to deoxycorticosterone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Mineralocorticoid receptor | polymer | 256 | 29675.3 | 3 | UniProt (P08235) Pfam (PF00104) | Homo sapiens (human) | MR |
| 2 | D, E, F (A, B, C) | DESOXYCORTICOSTERONE | non-polymer | 330.5 | 3 | Chemie (1CA) PubChem (6166) PubChem (223578) PubChem (667475) PubChem (1403452) PubChem (1403453) PubChem (1403454) PubChem (5316556) PubChem (6604197) PubChem (6984615) PubChem (12303995) PubChem (18530239) PubChem (23902378) PubChem (23955946) PubChem (40543501) PubChem (44135506) PubChem (44659452) PubChem (23900052) PubChem (40543496) PubChem (657194) PubChem (51578076) PubChem (154559530) PubChem (162968029) PubChem (73707523) PubChem (124303801) PubChem (124506965) PubChem (124770616) PubChem (124917358) PubChem (129162682) | |||
| 3 | G, H, I (A, B, C) | water | water | 18.0 | 381 | Chemie (HOH) |
Sequence modifications
A, B, C: 731 - 984 (UniProt: P08235)
| PDB | External Database | Details |
|---|---|---|
| Gly 729 | - | cloning artifact |
| Ser 730 | - | cloning artifact |
| Ala 910 | Cys 910 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 89026.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 991.4 | |
| All* | Total formula weight | 90017.4 |
