2ABI
Crystal structure of the human mineralocorticoid receptor ligand-binding domain bound to deoxycorticosterone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Mineralocorticoid receptor | polymer | 256 | 29675.3 | 3 | UniProt (P08235) Pfam (PF00104) | Homo sapiens (human) | MR |
| 2 | D, E, F (A, B, C) | DESOXYCORTICOSTERONE | non-polymer | 330.5 | 3 | Chemie (1CA) | |||
| 3 | G, H, I (A, B, C) | water | water | 18.0 | 381 | Chemie (HOH) |
Sequence modifications
A, B, C: 731 - 984 (UniProt: P08235)
| PDB | External Database | Details |
|---|---|---|
| Gly 729 | - | cloning artifact |
| Ser 730 | - | cloning artifact |
| Ala 910 | Cys 910 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 89026.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 991.4 | |
| All* | Total formula weight | 90017.4 |
