2ABI
Crystal structure of the human mineralocorticoid receptor ligand-binding domain bound to deoxycorticosterone
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 1CA A 1001 |
| Chain | Residue |
| A | LEU769 |
| A | PHE941 |
| A | CYS942 |
| A | THR945 |
| A | VAL954 |
| A | PHE956 |
| A | ASN770 |
| A | ALA773 |
| A | GLN776 |
| A | MET807 |
| A | SER810 |
| A | ARG817 |
| A | MET852 |
| A | LEU938 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 1CA B 2001 |
| Chain | Residue |
| B | LEU769 |
| B | ASN770 |
| B | ALA773 |
| B | GLN776 |
| B | MET807 |
| B | SER810 |
| B | ARG817 |
| B | PHE829 |
| B | PHE941 |
| B | CYS942 |
| B | THR945 |
| B | VAL954 |
| B | PHE956 |
| B | HOH4002 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE 1CA C 3001 |
| Chain | Residue |
| C | LEU769 |
| C | ASN770 |
| C | LEU772 |
| C | ALA773 |
| C | GLN776 |
| C | MET807 |
| C | SER810 |
| C | LEU814 |
| C | ARG817 |
| C | PHE829 |
| C | PHE941 |
| C | CYS942 |
| C | THR945 |
| C | VAL954 |
| C | PHE956 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 9 |
| Details | Region: {"description":"Important for coactivator binding"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15908963","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15967794","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1YA3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AA5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AA6","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15967794","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2AA5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AA6","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
