2AAZ
Cryptococcus neoformans thymidylate synthase complexed with substrate and an antifolate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Thymidylate synthase | polymer | 317 | 35912.0 | 16 | UniProt (P45351) Pfam (PF00303) UniProt (by SIFTS) (P0CS12) | Filobasidiella neoformans | TS, TSase |
| 2 | AA, CA, EA, GA, HA... (F, G, H, I, J...) | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE | non-polymer | 308.2 | 16 | Chemie (UMP) PubChem (688) PubChem (65063) PubChem (57164254) PubChem (446899) PubChem (446900) PubChem (71773959) PubChem (92144438) PubChem (92209480) PubChem (92209481) PubChem (92209482) PubChem (92449733) PubChem (133126534) | |||
| 3 | BA, DA, FA, R, T... (F, G, H, A, B...) | 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID | non-polymer | 477.5 | 8 | Chemie (CB3) | |||
| 4 | OA, PA, QA, RA, SA... (A, B, C, D, E...) | water | water | 18.0 | 1212 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 574591.6 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 8750.7 | |
| All* | Total formula weight | 583342.3 |
