2AAZ

Cryptococcus neoformans thymidylate synthase complexed with substrate and an antifolate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Thymidylate synthase	polymer	317	35912.0	16	UniProt (P45351) Pfam (PF00303) UniProt (by SIFTS) (P0CS12)	Filobasidiella neoformans	TS, TSase
2	AA, CA, EA, GA, HA... (F, G, H, I, J...)	2'-DEOXYURIDINE 5'-MONOPHOSPHATE	non-polymer		308.2	16	Chemie (UMP)
3	BA, DA, FA, R, T... (F, G, H, A, B...)	10-PROPARGYL-5,8-DIDEAZAFOLIC ACID	non-polymer		477.5	8	Chemie (CB3)
4	OA, PA, QA, RA, SA... (A, B, C, D, E...)	water	water		18.0	1212	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	574591.6
Non-Polymers*	Number of molecules	24
	Total formula weight	8750.7
All*	Total formula weight	583342.3

*Water molecules are not included.