2A66
Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | 5'-D(*GP*TP*TP*CP*AP*AP*GP*GP*CP*CP*AP*G)-3' | polymer | 12 | 3687.4 | 1 | Homo sapiens (human) | ||
| 2 | B (C) | 5'-D(*CP*TP*GP*GP*CP*CP*TP*TP*GP*AP*AP*C)-3' | polymer | 12 | 3638.4 | 1 | Homo sapiens (human) | ||
| 3 | C (A) | Orphan nuclear receptor NR5A2 | polymer | 113 | 13209.4 | 1 | UniProt (O00482) Pfam (PF00105) | Homo sapiens (human) | Alpha-1-fetoprotein transcription factor, Hepatocytic transcription factor, B1-binding factor, hB1F, CYP7A1 promoter binding factor |
| 4 | D, E (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | F (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 6 | G, H, I (B, C, A) | water | water | 18.0 | 86 | Chemie (HOH) |
Sequence modifications
A: 79 - 187 (UniProt: O00482)
| PDB | External Database | Details |
|---|---|---|
| Gly 75 | - | cloning artifact |
| Glu 76 | - | cloning artifact |
| Phe 77 | - | cloning artifact |
| Gly 78 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 20535.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 189.9 | |
| All* | Total formula weight | 20725.0 |
