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2A59

Structure of 6,7-Dimethyl-8-ribityllumazine synthase from Schizosaccharomyces pombe mutant W27Y with bound ligand 5-nitroso-6-ribitylamino-2,4(1H,3H)-pyrimidinedione

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E
(A, B, C, D, E)
6,7-dimethyl-8-ribityllumazine synthasepolymer15917183.85UniProt (Q9UUB1)
Pfam (PF00885)
Schizosaccharomyces pombe (fission yeast)DMRL synthase, Lumazine synthase, Riboflavin synthase beta chain
2F, H, J, L, N
(A, B, C, D, E)
PHOSPHATE IONnon-polymer95.05Chemie (PO4)
3G, I, K, M, O
(A, B, C, D, E)
5-NITROSO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONEnon-polymer290.25Chemie (LMZ)
4P, Q, R, S, T
(A, B, C, D, E)
waterwater18.058Chemie (HOH)
Sequence modifications
A, B, C, D, E: 1 - 159 (UniProt: Q9UUB1)
PDBExternal DatabaseDetails
Tyr 27Trp 27engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight85918.8
Non-Polymers*Number of molecules10
Total formula weight1926.0
All*Total formula weight87844.8
*Water molecules are not included.

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PDB entries from 2025-06-18

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