2A1T

Structure of the human MCAD:ETF E165betaA complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Acyl-CoA dehydrogenase, medium-chain specific, mitochondrial precursor	polymer	421	46648.3	4	UniProt (P11310) Pfam (PF02771) Pfam (PF02770) Pfam (PF00441)	Homo sapiens (human)	MCAD
2	E (R)	Electron transfer flavoprotein alpha-subunit, mitochondrial precursor	polymer	333	35121.5	1	UniProt (P13804) Pfam (PF01012) Pfam (PF00766)	Homo sapiens (human)	Alpha-ETF
3	F (S)	Electron transfer flavoprotein beta-subunit	polymer	255	27827.6	1	UniProt (P38117) Pfam (PF01012)	Homo sapiens (human)	Beta-ETF
4	G, H, I, J, K (A, B, C, D, R)	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	5	Chemie (FAD)
5	L (S)	ADENOSINE MONOPHOSPHATE	non-polymer		347.2	1	Chemie (AMP) PubChem (16397049) PubChem (16760266) PubChem (40459109) PubChem (46875232) PubChem (40467049) PubChem (40469468) PubChem (44348067) PubChem (45358029) PubChem (177678969) PubChem (6083) PubChem (46874558) PubChem (1549371) PubChem (92144436) PubChem (57358045) PubChem (12358354) PubChem (57879893) PubChem (57879902) PubChem (224) PubChem (122197642) PubChem (34768) PubChem (83862) PubChem (446048) PubChem (515384) PubChem (638042) PubChem (5316444) PubChem (5742864) PubChem (12163610) PubChem (12358355) PubChem (162290139) PubChem (162946266) PubChem (171699505)
6	M, N, O, P, Q... (A, B, C, D, R...)	water	water		18.0	64	Chemie (HOH)

Sequence modifications

S: 1 - 255 (UniProt: P38117)

PDB	External Database	Details
Ala 165	Glu 165	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	249542.2
Non-Polymers*	Number of molecules	6
	Total formula weight	4275.0
All*	Total formula weight	253817.2

*Water molecules are not included.