23XK

Cryo-EM structure of human sodium/proton antiporter NHE1 in complex with Cariporide in an outward-open conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Sodium/hydrogen exchanger 1	polymer	815	90866.8	2	UniProt (P19634)	Homo sapiens (human)	APNH,Na(+)/H(+) antiporter,amiloride-sensitive,Na(+)/H(+) exchanger 1,NHE-1,Solute carrier family 9 member 1
2	C, D (A, B)	N-[bis(azanyl)methylidene]-3-methylsulfonyl-4-propan-2-yl-benzamide	non-polymer		283.3	2	Chemie (HG0) PubChem (151172)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	181733.5
Non-Polymers*	Number of molecules	2
	Total formula weight	566.7
All*	Total formula weight	182300.2

*Water molecules are not included.