1ZSV

Crystal structure of human NADP-dependent leukotriene B4 12-hydroxydehydrogenase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	NADP-dependent leukotriene B4 12-hydroxydehydrogenase	polymer	349	38229.2	4	UniProt (Q14914) Pfam (PF16884) Pfam (PF00107)	Homo sapiens (human)
2	E, F, G, H, I... (A, B, C, D)	CHLORIDE ION	non-polymer		35.5	22	Chemie (CL)
3	AA, BA, CA, DA (A, B, C, D)	water	water		18.0	315	Chemie (HOH)

Sequence modifications

A, B, C, D: 4 - 329 (UniProt: Q14914)

PDB	External Database	Details
Met -19	-	cloning artifact
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
Ser -12	-	cloning artifact
Ser -11	-	cloning artifact
Gly -10	-	cloning artifact
Val -9	-	cloning artifact
Asp -8	-	cloning artifact
Leu -7	-	cloning artifact
Gly -6	-	cloning artifact
Thr -5	-	cloning artifact
Glu -4	-	cloning artifact
Asn -3	-	cloning artifact
Leu -2	-	cloning artifact
Tyr -1	-	cloning artifact
Phe 0	-	cloning artifact
Gln 1	-	cloning artifact
Ser 2	-	cloning artifact
Met 3	-	cloning artifact

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	152916.7
Non-Polymers*	Number of molecules	22
	Total formula weight	780.0
All*	Total formula weight	153696.6

*Water molecules are not included.