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1ZKL

Multiple Determinants for Inhibitor Selectivity of Cyclic Nucleotide Phosphodiesterases

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7Apolymer35340763.11UniProt (Q13946)
Pfam (PF00233)
Homo sapiens (human)HCP1, TM22
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
4D
(A)
3-ISOBUTYL-1-METHYLXANTHINEnon-polymer222.21Chemie (IBM)
5E
(A)
waterwater18.0289Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight40763.1
Non-Polymers*Number of molecules3
Total formula weight312.0
All*Total formula weight41075.1
*Water molecules are not included.

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PDB entries from 2025-07-16

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