1ZBH
3'-end specific recognition of histone mRNA stem-loop by 3'-exonuclease
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (F, E) | 5'-R(*CP*CP*GP*GP*CP*UP*CP*UP*UP*UP*UP*CP*AP*GP*AP*GP*CP*CP*GP*G)-3' | polymer | 20 | 6351.8 | 2 | |||
| 2 | C, D, E, F (A, B, C, D) | 3'-5' exonuclease ERI1 | polymer | 299 | 34655.0 | 4 | UniProt (Q8IV48) Pfam (PF02037) Pfam (PF00929) | Homo sapiens (human) | Eri-1 homolog, Histone mRNA 3' end-specific exoribonuclease, Protein 3'hExo, HEXO |
| 3 | G, H, J, K, M... (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) PubChem (888) | |||
| 4 | I, L, O, R (A, B, C, D) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 4 | Chemie (AMP) PubChem (16397049) PubChem (16760266) PubChem (224) PubChem (40467049) PubChem (40469468) PubChem (34768) PubChem (44348067) PubChem (83862) PubChem (45358029) PubChem (46874558) PubChem (40459109) PubChem (57358045) PubChem (57879893) PubChem (57879902) PubChem (46875232) PubChem (446048) PubChem (515384) PubChem (638042) PubChem (177678969) PubChem (6083) PubChem (1549371) PubChem (5316444) PubChem (92144436) PubChem (5742864) PubChem (122197642) PubChem (12358354) PubChem (12163610) PubChem (12358355) PubChem (162290139) PubChem (162946266) PubChem (171699505) | |||
| 5 | S, T, U, V, W (F, A, B, C, D) | water | water | 18.0 | 18 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 51 - 349 (UniProt: Q8IV48)
| PDB | External Database | Details |
|---|---|---|
| Leu 213 | Trp 212 | engineered mutation |
| Asn 293 | His 292 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 151323.8 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1583.3 | |
| All* | Total formula weight | 152907.1 |
