1ZBH

3'-end specific recognition of histone mRNA stem-loop by 3'-exonuclease

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (F, E)	5'-R(*CP*CP*GP*GP*CP*UP*CP*UP*UP*UP*UP*CP*AP*GP*AP*GP*CP*CP*GP*G)-3'	polymer	20	6351.8	2
2	C, D, E, F (A, B, C, D)	3'-5' exonuclease ERI1	polymer	299	34655.0	4	UniProt (Q8IV48) Pfam (PF02037) Pfam (PF00929)	Homo sapiens (human)	Eri-1 homolog, Histone mRNA 3' end-specific exoribonuclease, Protein 3'hExo, HEXO
3	G, H, J, K, M... (A, B, C, D)	MAGNESIUM ION	non-polymer		24.3	8	Chemie (MG)
4	I, L, O, R (A, B, C, D)	ADENOSINE MONOPHOSPHATE	non-polymer		347.2	4	Chemie (AMP)
5	S, T, U, V, W (F, A, B, C, D)	water	water		18.0	18	Chemie (HOH)

Sequence modifications

A, B, C, D: 51 - 349 (UniProt: Q8IV48)

PDB	External Database	Details
Leu 213	Trp 212	engineered mutation
Asn 293	His 292	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	151323.8
Non-Polymers*	Number of molecules	12
	Total formula weight	1583.3
All*	Total formula weight	152907.1

*Water molecules are not included.