1ZBH
3'-end specific recognition of histone mRNA stem-loop by 3'-exonuclease
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | F, E | 5'-R(*CP*CP*GP*GP*CP*UP*CP*UP*UP*UP*UP*CP*AP*GP*AP*GP*CP*CP*GP*G)-3' | polymer | 20 | 6351.8 | 2 | |||
| 2 | A, B, C, D | 3'-5' exonuclease ERI1 | polymer | 299 | 34655.0 | 4 | UniProt (Q8IV48) Pfam (PF02037) Pfam (PF00929) In PDB | Homo sapiens (human) | Eri-1 homolog, Histone mRNA 3' end-specific exoribonuclease, Protein 3'hExo, HEXO |
| 3 | A, B, C, D | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) | |||
| 4 | A, B, C, D | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 4 | Chemie (AMP) | |||
| 5 | water | water | 18.0 | 18 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 51 - 349 (UniProt: Q8IV48)
| PDB | External Database | Details |
|---|---|---|
| Leu 213 | Trp 212 | engineered mutation |
| Asn 293 | His 292 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 151323.8 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1583.3 | |
| All* | Total formula weight | 152907.1 |
