1YW2
Mutated Mus Musculus P38 Kinase (mP38)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Mitogen-activated protein kinase 14 | polymer | 360 | 41292.1 | 1 | UniProt (P47811) Pfam (PF00069) In PDB | Mus musculus (house mouse) | Mitogen-activated protein kinase p38alpha, MAP kinase p38alpha, CRK1 |
| 2 | A | 2-(ETHOXYMETHYL)-4-(4-FLUOROPHENYL)-3-[2-(2-HYDROXYPHENOXY)PYRIMIDIN-4-YL]ISOXAZOL-5(2H)-ONE | non-polymer | 423.4 | 1 | Chemie (PGJ) | |||
| 3 | water | water | 18.0 | 195 | Chemie (HOH) |
Sequence modifications
A: 1001 - 1360 (UniProt: P47811)
| PDB | External Database | Details |
|---|---|---|
| Ala 1180 | Thr 179 | engineered mutation |
| Phe 1182 | Tyr 181 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41292.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 423.4 | |
| All* | Total formula weight | 41715.5 |
