1YGU

Crystal structure of the tandem phosphatase domains of RPTP CD45 with a pTyr peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Leukocyte common antigen	polymer	610	71500.6	2	UniProt (P08575) Pfam (PF00102)	Homo sapiens (human)	L-CA, CD45 antigen, T200
2	C, D (C, D)	Polyoma Middle T antigen	polymer	4	546.5	2	UniProt (P03077)

Sequence modifications

A, B: 599 - 1208 (UniProt: P08575)

PDB	External Database	Details
Mse 603	Met 626	modified residue
Pro 627	Leu 650	variant
Mse 714	Met 737	modified residue
Mse 725	Met 748	modified residue
Mse 744	Met 767	modified residue
Ser 828	Cys 851	engineered mutation
Mse 844	Met 867	modified residue
Mse 870	Met 893	modified residue
Mse 907	Met 930	modified residue
Mse 999	Met 1022	modified residue
Mse 1007	Met 1030	modified residue
Mse 1024	Met 1047	modified residue
Mse 1035	Met 1058	modified residue
Mse 1115	Met 1138	modified residue
Leu 1184	Pro 1207	variant
Mse 1186	Met 1209	modified residue

C, D: 2002 - 2005 (UniProt: P03077)

PDB	External Database	Details
Ptr 2004	Tyr 250	modified residue

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	144094.2
All*	Total formula weight	144094.2

*Water molecules are not included.