1Y8Q
SUMO E1 ACTIVATING ENZYME SAE1-SAE2-MG-ATP COMPLEX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Ubiquitin-like 1 activating enzyme E1A | polymer | 346 | 38499.8 | 2 | UniProt (Q9UBE0) Pfam (PF00899) | Homo sapiens (human) | SUMO-1 activating enzyme subunit 1 |
| 2 | B, D (B, D) | Ubiquitin-like 2 activating enzyme E1B | polymer | 640 | 71282.4 | 2 | UniProt (Q9UBT2) Pfam (PF00899) Pfam (PF14732) Pfam (PF16195) | Homo sapiens (human) | SUMO-1 activating enzyme subunit 2; Anthracycline-associated resistance ARX; HRIHFB2115 |
| 3 | E, H (B, D) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | F, I (B, D) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | G, J (B, D) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
| 6 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 820 | Chemie (HOH) |
Sequence modifications
B, D: 1 - 640 (UniProt: Q9UBT2)
| PDB | External Database | Details |
|---|---|---|
| Ala 173 | Cys 173 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 219564.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1193.8 | |
| All* | Total formula weight | 220758.3 |
