1XK4
Crystal structure of human calprotectin(S100A8/S100A9)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, E, F, I... (A, B, E, F, I...) | Calgranulin A | polymer | 93 | 10837.5 | 6 | UniProt (P05109) Pfam (PF01023) | Homo sapiens (human) | S100 calcium-binding protein a8, s100a8, migration inhibitory factor-related protein 8, MRP-8, P8, cystic fibrosis antigen, cfag, leukocyte L1 complex light chain, calprotectin L1L |
| 2 | C, D, G, H, K... (C, D, G, H, K...) | Calgranulin B | polymer | 113 | 13116.8 | 6 | UniProt (P06702) Pfam (PF01023) | Homo sapiens (human) | S100 calcium-binding protein A9, S100A9, migration inhibitory factor-related protein 14, MRP-14, P14, leucocyte L1 complex heavy chain, calprotectin L1H subunit |
| 3 | CA, DA, EA, FA, GA... (G, H, I, J, K...) | CALCIUM ION | non-polymer | 40.1 | 24 | Chemie (CA) | |||
| 4 | AA, KA, O, R (F, J, A, B) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 5 | BA (F) | CITRATE ANION | non-polymer | 189.1 | 1 | Chemie (FLC) | |||
| 6 | AB, PA, QA, RA, SA... (L, A, B, C, D...) | water | water | 18.0 | 1059 | Chemie (HOH) |
Sequence modifications
A, B, E, F, I, J: 1 - 93 (UniProt: P05109)
C, D, G, H, K, L: 2 - 114 (UniProt: P06702)
| PDB | External Database | Details |
|---|---|---|
| Ser 42 | Cys 42 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ser 3 | Cys 3 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 143725.3 | |
| Non-Polymers* | Number of molecules | 29 |
| Total formula weight | 1292.8 | |
| All* | Total formula weight | 145018.1 |
