1XG5

Structure of human putative dehydrogenase MGC4172 in complex with NADP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	ARPG836	polymer	279	30466.5	4	UniProt (Q6UWP2) Pfam (PF00106)	Homo sapiens (human)	MGC4172 gene product
2	E, G, H, J (A, B, C, D)	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	4	Chemie (NAP)
3	F, I, K (A, C, D)	ACETIC ACID	non-polymer		60.1	3	Chemie (ACY)
4	L, M, N, O (A, B, C, D)	water	water		18.0	859	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 256 (UniProt: Q6UWP2)

PDB	External Database	Details
Gly -20	-	expression tag
Ser -19	-	expression tag
Ser -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
Ser -11	-	expression tag
Ser -10	-	expression tag
Gly -9	-	expression tag
Arg -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Gly -1	-	expression tag
His 0	-	expression tag
Gly 257	-	cloning artifact
Ser 258	-	cloning artifact

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	121866.1
Non-Polymers*	Number of molecules	7
	Total formula weight	3153.8
All*	Total formula weight	125019.8

*Water molecules are not included.