1X7A
Porcine Factor IXa Complexed to 1-{3-[amino(imino)methyl]phenyl}-N-[4-(1H-benzimidazol-1-yl)-2-fluorophenyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | C | Coagulation Factor IXa | polymer | 235 | 26054.6 | 1 | UniProt (P16293) Pfam (PF00089) In PDB | Sus scrofa (pig) | Christmas factor |
| 2 | L | Coagulation Factor IX, light chain | polymer | 146 | 16456.4 | 1 | UniProt (P16293) Pfam (PF00594) Pfam (PF00008) Pfam (PF14670) In PDB | Sus scrofa (pig) | mature porcine factor IX |
| 3 | C | 1-{3-[AMINO(IMINO)METHYL]PHENYL}-N-[4-(1H-BENZIMIDAZOL-1-YL)-2-FLUOROPHENYL]-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-5-CARBOXAMIDE | non-polymer | 507.4 | 1 | Chemie (187) |
Sequence modifications
C: 16 - 245 (UniProt: P16293)
| PDB | External Database | Details |
|---|---|---|
| Phe 174 | Val 206 | SEE REMARK 999 |
| Gln 192 | Leu 226 | SEE REMARK 999 |
| Ile 238 | - | SEE REMARK 999 |
| Lys 239 | - | SEE REMARK 999 |
| Glu 240 | - | SEE REMARK 999 |
| Lys 241 | - | SEE REMARK 999 |
| Thr 242 | - | SEE REMARK 999 |
| Lys 243 | - | SEE REMARK 999 |
| Leu 244 | - | SEE REMARK 999 |
| Thr 245 | - | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42511.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 507.4 | |
| All* | Total formula weight | 43018.5 |
